Epigallocatechin‐3‐gallate sensitises multidrug‐resistant oral carcinoma xenografts to vincristine sulfate
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چکیده
منابع مشابه
Pressor mechanism of vincristine sulfate.
Studying the pharmacological activities of vincristine sulfate (VCR), one of the alkaloids isolated from Vinca rosea Linn. by Svoboda et al. (1), Anderson et al. (2) observed the pressor, positive chronotropic and re spiratory stimulating effects in dogs. Since no action mechanisms of these pharmacological effects were reported, the authors attempted to clarify its pressor mechanisms. Pressor e...
متن کاملPreventing vincristine sulfate medication errors.
PURPOSE/OBJECTIVES To review the clinical pharmacology of vincristine sulfate, describe three types of medication errors associated with its use, and suggest strategies for vincristine sulfate medication error prevention. DATA SOURCES Published books and journal articles, online newsletters and documents, pharmaceutical manufacturers package inserts, and personal experience. DATA SYNTHESIS ...
متن کاملPharmacokinetics of Vincristine Sulfate in Adult Cancer Patients1
Vincristine concentration in serum from 1 min to 72 hr was measured by radioimmunoassay in 14 patients with cancers following i.v. bolus injection of Vincristine sulfate at 0.45 to 1.30 mg/sq m. The pharmacokinetic data were analyzed by a nonlinear least-square regression program NONLIN. A threecompartmental open model fitted the raw data better than a two-compartmental model. The mean half-liv...
متن کاملPharmacokinetics of vincristine sulfate in adult cancer patients.
Vincristine concentration in serum from 1 min to 72 hr was measured by radioimmunoassay in 14 patients with cancers following i.v. bolus injection of vincristine sulfate at 0.45 to 1.30 mg/sq m. The pharmacokinetic data were analyzed by a nonlinear least-square regression program NONLIN. A three-compartmental open model fitted the raw data better than a two-compartmental model. The mean half-li...
متن کاملVincristine sulfate liposomal injection for acute lymphoblastic leukemia
Vincristine (VCR) is one of the most extensively used cytotoxic compounds in hemato-oncology. VCR is particularly important for the treatment of acute lymphoblastic leukemia (ALL), a disease that accounts for approximately one-third of all childhood cancer diagnoses. VCR's full therapeutic potential has been limited by dose-limiting neurotoxicity, classically resulting in autonomic and peripher...
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ژورنال
عنوان ژورنال: FEBS Open Bio
سال: 2020
ISSN: 2211-5463,2211-5463
DOI: 10.1002/2211-5463.12905